What is the sequence of the -10 region of prokaryotic promoters?

The -10 region of prokaryotic promoters, often referred to as the Pribnow box, is typically characterized by the consensus sequence TATAAT. This sequence is critical because it is recognized by RNA polymerase during the initiation of transcription. The presence of TATAAT provides specific binding sites and helps to position the RNA polymerase in the correct orientation for the transcription process to begin.

This recognition is an essential step in the transcription machinery of prokaryotes, enabling the RNA polymerase to unwind the DNA and synthesize RNA. Other sequences, while they may play essential roles in different aspects of gene regulation or promoter function, do not represent the -10 region specifically.